Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.62 |
| ▸ | BCHE | P06276 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11351471 | 0.90 | KDM4E (0.54) | ACHEBCHEKDM4EDRD2DRD4 | |
| SCHEMBL11084557 | 0.89 | ACHE (0.58) | ACHEBCHEKDM4EDRD2DRD3 | |
| SCHEMBL11343643 | 0.84 | MAOB (0.52) | ACHEBCHE | |
| SCHEMBL11347971 | 0.83 | DRD2 (0.58) | ACHEBCHEKDM4EDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL10568463 | 0.79 | DRD2 (0.66) | DRD2DRD4DRD3HTR1ASIGMAR1 | |
| SCHEMBL11066530 | 0.78 | MAOB (0.62) | ACHEBCHESIGMAR1 | |
| SCHEMBL11342118 | 0.78 | DRD2 (0.63) | DRD2DRD3HTR1A | |
| SCHEMBL11345831 | 0.77 | PDE3B (0.50) | ACHEBCHEKDM4EDRD2DRD4 | |
| SCHEMBL11345865 | 0.77 | ALOX5 (0.52) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL15971627 | 0.77 | ACHE (1.00) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4234585-A | ANTIALLERGENS, HYPOTENSIVE | BOEHRINGER MANNHEIM GMBH (DE) | 1980-11-18 | — | — | US | disclosed |
| EP-0006506-A1 | Carbostyrile derivatives, processes for their preparation and pharmaceutical compositions containing them | Roche Diagnostics GmbH (DE) | 1980-01-09 | — | — | EP | disclosed |