Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11452987 | 0.98 | LMNA (0.40) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL11474573 | 0.98 | LMNA (0.40) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL11453015 | 0.92 | LMNA (0.38) | LMNAKISS1RBLM | |
| SCHEMBL4202303 | 0.87 | ALDH1A1 (0.34) | LMNAMEN1XBP1KMT2ANPSR1 | |
| SCHEMBL4209411 | 0.84 | SIGMAR1 (0.37) | LMNATRPV1TRPA1MEN1XBP1 | |
| SCHEMBL4202305 | 0.84 | SIGMAR1 (0.37) | LMNATRPV1TRPA1MEN1XBP1 | |
| SCHEMBL6695787 | 0.81 | — | — | |
| SCHEMBL4211600 | 0.81 | TSHR (0.32) | LMNAMEN1XBP1KMT2ANPSR1 | |
| SCHEMBL16306468 | 0.79 | TRPV1 (0.43) | LMNATRPV1TRPA1BLMMEN1 | |
| SCHEMBL12039773 | 0.79 | LMNA (0.46) | LMNAKDM4CKDM4APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4223138-A | VAPORIZATION, CONDENSATION, RETARDING FLOW TO REACTION ZONE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-16 | — | — | US | disclosed |