Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 5/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | FABP2 | P12104 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417184 | 0.95 | PPARA (0.44) | PPARACYP1A2MEN1CYP3A4CYP2D6 | |
| SCHEMBL14319122 | 0.79 | ALDH1A1 (0.39) | PPARACYP1A2MEN1MAPTKMT2A | |
| SCHEMBL10642060 | 0.77 | ESR1 (0.42) | KMT2A | |
| SCHEMBL10147522 | 0.72 | LMNA (0.38) | MEN1CYP2D6MAPTCYP2C19KMT2A | |
| SCHEMBL16139495 | 0.72 | MEN1 (0.39) | PPARACYP1A2MEN1CYP3A4CYP2D6 | |
| SCHEMBL12519422 | 0.70 | MEN1 (0.38) | CYP1A2MEN1CYP2C19KMT2ACNR1 | |
| SCHEMBL12519429 | 0.70 | MAOB (0.48) | CYP1A2MEN1CYP3A4CYP2C19KMT2A | |
| SCHEMBL11279619 | 0.69 | PTGES2 (0.53) | PPARACYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL13950432 | 0.69 | MEN1 (0.37) | MEN1CYP3A4KMT2A | |
| SCHEMBL11836094 | 0.68 | KMT2A (0.52) | PPARACYP1A2MEN1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4191776-A | ANTITHROMBOTICS, ANTICHOLESTEREMICS, ANTICOAGULANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-03-04 | — | — | US | disclosed |