Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11458342 | 0.79 | HMGB1 (0.39) | SMN1; SMN2POLBMEN1MAPTHTT | |
| SCHEMBL423686 | 0.77 | AKR1C4 (0.60) | HSD17B10HIF1AHPGDSMN1; SMN2POLB | |
| SCHEMBL11456323 | 0.76 | BCL2 (0.44) | MCL1ALDH1A1 | |
| SCHEMBL11457691 | 0.74 | PRKCI (0.36) | HIF1AMEN1MAPTKMT2ALMNA | |
| SCHEMBL11458448 | 0.72 | BCL2 (0.50) | POLBGPR35HDAC1HDAC6 | |
| SCHEMBL11469231 | 0.72 | TYR (0.37) | HPGDMEN1MAPTHTTKMT2A | |
| SCHEMBL8822888 | 0.72 | HSD17B10 (0.76) | HSD17B10HIF1AHPGDCYP2C19SMN1; SMN2 | |
| SCHEMBL11457692 | 0.70 | ALOX5 (0.40) | HPGDPOLBMEN1MAPTHTT | |
| SCHEMBL11466492 | 0.70 | ALOX5 (0.40) | HPGDPOLBMEN1MAPTHTT | |
| SCHEMBL28521133 | 0.70 | TTR (0.56) | HSD17B10HIF1ACYP2C19SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225619-A | BACTERICIDES, FUNGICIDES | BOEHRINGER INGELHEIM GMBH (DE) | 1980-09-30 | — | — | US | disclosed |