Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11464682 | 0.79 | HSD17B10 (0.44) | HDAC6HDAC1MEN1MAPTKMT2A | |
| SCHEMBL11456323 | 0.79 | BCL2 (0.44) | GAACA1CA2 | |
| SCHEMBL11457691 | 0.78 | PRKCI (0.36) | HDAC4HDAC6HDAC1HDAC3MEN1 | |
| SCHEMBL11469231 | 0.75 | TYR (0.37) | MEN1MAPTKMT2AHTTMLYCD | |
| SCHEMBL11466492 | 0.73 | ALOX5 (0.40) | MEN1MAPTKMT2AHTTGAA | |
| SCHEMBL11458745 | 0.72 | HSPA5 (0.36) | HMGB1CXCL12HDAC4HDAC6HDAC1 | |
| SCHEMBL11458448 | 0.72 | BCL2 (0.50) | HDAC4HDAC6HDAC1HDAC3POLB | |
| SCHEMBL13924151 | 0.69 | PPARA (0.38) | HDAC4HDAC6HDAC1MEN1MAPT | |
| SCHEMBL20756339 | 0.69 | CES1 (0.38) | HTTP2RX1ESR1ESR2CA1 | |
| SCHEMBL26606973 | 0.67 | ALDH1A1 (0.33) | HTTP2RX1ESR1ESR2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225619-A | BACTERICIDES, FUNGICIDES | BOEHRINGER INGELHEIM GMBH (DE) | 1980-09-30 | — | — | US | disclosed |