Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11457691 | 0.77 | PRKCI (0.36) | PTPN1HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL11469231 | 0.74 | TYR (0.37) | ALOX5 | |
| SCHEMBL28707306 | 0.73 | PTPN1 (0.73) | BCL2PTPN1PTPN2PTPN6BCL2L1 | |
| SCHEMBL11466492 | 0.72 | ALOX5 (0.40) | BCL2L1ALOX5POLB | |
| SCHEMBL11458342 | 0.72 | HMGB1 (0.39) | HDAC3HDAC4HDAC1HDAC6POLB | |
| SCHEMBL11464682 | 0.72 | HSD17B10 (0.44) | HDAC1HDAC6POLBGPR35 | |
| SCHEMBL4906876 | 0.72 | PTPN1 (0.60) | BCL2PTPN1PTPN2PTPN6BCL2L1 | |
| SCHEMBL11458745 | 0.69 | HSPA5 (0.36) | BCL2PTPN1PTPN2PTPN6HDAC3 | |
| SCHEMBL11208758 | 0.69 | PTPN1 (0.57) | BCL2PTPN1PTPN2PTPN6BCL2L1 | |
| SCHEMBL15314345 | 0.69 | BCL2 (0.61) | BCL2PTPN1PTPN2PTPN6BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225619-A | BACTERICIDES, FUNGICIDES | BOEHRINGER INGELHEIM GMBH (DE) | 1980-09-30 | — | — | US | disclosed |