Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814077 | 0.90 | MAPT (0.67) | MAPTALDH1A1LMNAKDM4EADRB1 | |
| SCHEMBL11416119 | 0.86 | ALDH1A1 (0.47) | MAPTALDH1A1LMNAKDM4EADRB1 | |
| SCHEMBL11571275 | 0.86 | MAPT (0.67) | MAPTALDH1A1LMNAKDM4EADRB1 | |
| SCHEMBL9620020 | 0.86 | MAPT (0.69) | MAPTALDH1A1LMNAADRB1ADRB3 | |
| SCHEMBL11674318 | 0.83 | ALDH1A1 (0.49) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10889271 | 0.82 | MAPT (0.77) | MAPTALDH1A1LMNAADRB1ADRB3 | |
| SCHEMBL9327473 | 0.80 | FAAH (0.46) | MAPTALDH1A1LMNAKDM4EADRB1 | |
| SCHEMBL28332833 | 0.78 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9661011 | 0.77 | MAPT (0.78) | MAPTALDH1A1LMNAADRB1ADRB3 | |
| SCHEMBL10383129 | 0.77 | MEN1 (0.69) | MAPTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4189427-A | Azo dyestuffs from benzene diazo component fused to an aliphatic ring and containing two cyano substituents ortho to the azo group | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | disclosed |