Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | UNG | P13051 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578294 | 0.94 | KMT2A (0.51) | MEN1KMT2AALDH1A1UNGCREBBP | |
| SCHEMBL29957449 | 0.85 | UNG (0.68) | MEN1KMT2AALDH1A1UNGCREBBP | |
| SCHEMBL1482839 | 0.85 | UNG (0.68) | MEN1KMT2AALDH1A1UNGCREBBP | |
| SCHEMBL6048207 | 0.83 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1UNGCREBBP | |
| SCHEMBL28167538 | 0.83 | KMT2A (0.46) | MEN1KMT2AALDH1A1UNGCREBBP | |
| SCHEMBL5950219 | 0.83 | MEN1 (0.46) | MEN1KMT2AALDH1A1UNGCREBBP | |
| SCHEMBL4153267 | 0.83 | TDP1 (0.50) | MEN1KMT2AALDH1A1UNGCREBBP | |
| SCHEMBL14435609 | 0.83 | MEN1 (0.46) | MEN1KMT2AALDH1A1UNGCREBBP | |
| SCHEMBL29838039 | 0.83 | TDP1 (0.50) | MEN1KMT2AALDH1A1UNGCREBBP | |
| SCHEMBL11770065 | 0.82 | TTR (0.59) | MEN1KMT2AUNGTDP1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233445-A | SYNERGISTIC WITH SULFA DRUGS AS BACTERICIDES AND ANTIPROTOZOA AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |
| US-4208520-A | BACTERICIDE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |