SCHEMBL14435609

SCHEMBL14435609

CC(=O)c1cccc(C=N)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
ALDH1A1 P00352 5/20 0.46
UNG P13051 1/20 0.46
CREBBP Q92793 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
NPC1 O15118 3/20 0.42
RAB9A P51151 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MAPT P10636 1/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
MAOB P27338 2/20 0.41
MAOA P21397 1/20 0.41
TTR P02766 2/20 0.40
HTT P42858 1/20 0.40
MAPK1 P28482 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11465197 0.83 MEN1 (0.49) MEN1KMT2AALDH1A1UNGCREBBP
SCHEMBL1482839 0.82 UNG (0.68) MEN1KMT2AALDH1A1UNGCREBBP
SCHEMBL29957449 0.82 UNG (0.68) MEN1KMT2AALDH1A1UNGCREBBP
SCHEMBL22366552 0.82 UNG (0.68) UNGTDP1TTR
SCHEMBL5950219 0.80 MEN1 (0.46) MEN1KMT2AALDH1A1UNGCREBBP
SCHEMBL29838039 0.80 TDP1 (0.50) MEN1KMT2AALDH1A1UNGCREBBP
SCHEMBL6048207 0.80 ALDH1A1 (0.46) MEN1KMT2AALDH1A1UNGCREBBP
SCHEMBL28167538 0.80 KMT2A (0.46) MEN1KMT2AALDH1A1UNGCREBBP
SCHEMBL4153267 0.80 TDP1 (0.50) MEN1KMT2AALDH1A1UNGCREBBP
SCHEMBL14231965 0.79 P4HB (0.56) MEN1KMT2AALDH1A1TDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3216820-B1 POLYARYLETHER KETONE IMIDE SULFONE ADHESIVES BOEING CO (US) 2020-09-23 EP disclosed
WO-2007086538-A1 RETARDATION PLATE, POLARIZER PLATE, AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPOTATION (JP) 2007-08-02 WO disclosed