Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | CBFB | Q13951 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11464920 | 0.87 | ADRA1A (0.61) | ADRA1ACHRM1GABRA1GABRA5GABRA3 | |
| SCHEMBL11462395 | 0.87 | CHRM1 (0.58) | ADRA1ACHRM1LMNAMEN1ALB | |
| SCHEMBL11469680 | 0.82 | MEN1 (0.53) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL11465381 | 0.81 | CCNE2 (0.49) | CCNE2CCNE1CDK2 | |
| SCHEMBL11461999 | 0.80 | GABRA1 (0.44) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL11473985 | 0.79 | GABRA1 (0.43) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL11481026 | 0.79 | LMNA (0.58) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| SCHEMBL11481670 | 0.79 | GABRA1 (0.42) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| SCHEMBL11463616 | 0.79 | GABRA1 (0.41) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL11481342 | 0.77 | CHRM1 (0.44) | CHRM1NPY5RGABRA1GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4232016-A | 3-Fluorobenzodiazepines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1980-11-04 | — | — | US | disclosed |