Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11447021 | 0.99 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1TSHRUSP2 | |
| SCHEMBL11608542 | 0.91 | KMT2A (0.52) | ALDH1A1KMT2AMEN1TSHRUSP2 | |
| Hydrochloric Acid SCHEMBL11456528 | 0.90 | KMT2A (0.51) | ALDH1A1KMT2AMEN1TSHRUSP2 | |
| SCHEMBL4931903 | 0.89 | ADRA1A (0.54) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL11454261 | 0.88 | HTR7 (0.56) | ALDH1A1KMT2AMEN1TSHRUSP2 | |
| SCHEMBL11465177 | 0.88 | HTR7 (0.56) | ALDH1A1KMT2AMEN1TSHRUSP2 | |
| SCHEMBL11456608 | 0.87 | HTR7 (0.47) | ALDH1A1KMT2AMEN1TSHRUSP2 | |
| SCHEMBL11446759 | 0.87 | HTR7 (0.47) | ALDH1A1KMT2AMEN1TSHRUSP2 | |
| SCHEMBL11447014 | 0.87 | HTR7 (0.55) | ALDH1A1KMT2AMEN1TSHRUSP2 | |
| SCHEMBL11446886 | 0.87 | HTR7 (0.55) | ALDH1A1KMT2AMEN1TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205173-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |
| US-4085107-A | ANALGESICS | PENNWALT CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |
| US-4060526-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |