SCHEMBL1146610

SCHEMBL1146610

NNc1cccc2c1[nH]c1ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 4/20 0.55
▸ JAK2 O60674 1/20 0.53
▸ TP53 P04637 1/20 0.53
▸ MAPT P10636 1/20 0.53
▸ HTT P42858 1/20 0.53
▸ KLK7 P49862 1/20 0.53
▸ PARP14 Q460N5 13/20 0.50
▸ ALDH1A1 P00352 1/20 0.50
▸ GPR3 P46089 1/20 0.50
▸ HSD17B10 Q99714 1/20 0.50
▸ GABRP O00591 1/20 0.48
▸ GABRD O14764 1/20 0.48
▸ GABRA1 P14867 1/20 0.48
▸ GABRB1 P18505 1/20 0.48
▸ GABRG2 P18507 1/20 0.48
▸ GABRB3 P28472 1/20 0.48
▸ GABRA5 P31644 1/20 0.48
▸ GABRA3 P34903 1/20 0.48
▸ GABRA2 P47869 1/20 0.48
▸ GABRB2 P47870 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9490444 0.83 KIF11 (0.59) KIF11JAK2TP53MAPTHTT
SCHEMBL29206609 0.80 JAK2 (0.57) KIF11JAK2TP53MAPTHTT
SCHEMBL20887128 0.80 KIF11 (0.60) KIF11JAK2TP53MAPTHTT
SCHEMBL30346387 0.77 MAPT (0.59) KIF11JAK2TP53MAPTHTT
SCHEMBL8415803 0.77 MAPT (0.59) KIF11JAK2TP53MAPTHTT
SCHEMBL31142015 0.77 JAK2 (0.50) KIF11JAK2TP53MAPTHTT
SCHEMBL8757524 0.76 PARP14 (0.55) KIF11JAK2TP53MAPTHTT
SCHEMBL28887355 0.76 KIF11 (0.59) KIF11JAK2TP53MAPTHTT
SCHEMBL9501877 0.76 KIF11 (0.50) KIF11JAK2TP53MAPTHTT
SCHEMBL27778673 0.76 JAK2 (0.53) KIF11JAK2TP53MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115448909-B N-carbazolyl-1H-pyrrole-2-carboxamide and application thereof as ligand in copper-catalyzed C-N coupling reaction 中山大学 2023-10-27 — — CN claimed
CN-115448909-A N-carbazolyl-1H-pyrrole-2-formamide and application thereof as ligand in copper-catalyzed C-N coupling reaction 中山大学 2022-12-09 — — CN claimed
US-6444385-B1 — — None — — US disclosed
JP-63061255-A — — None — — JP disclosed
CN-115448909-B N-carbazolyl-1H-pyrrole-2-carboxamide and application thereof as ligand in copper-catalyzed C-N coupling reaction 中山大学 2023-10-27 — — CN disclosed
CN-116478082-A Synthesis method of carbazolyl-containing Schiff base in eutectic solvent 陕西科技大学 2023-07-25 — — CN disclosed
CN-115448909-A N-carbazolyl-1H-pyrrole-2-formamide and application thereof as ligand in copper-catalyzed C-N coupling reaction 中山大学 2022-12-09 — — CN disclosed
CN-101794090-B Electrophtography photosensor and image processing system KYOCERA DOCUMENT SOLUTIONS INC (JP) 2016-01-20 — — CN disclosed
US-8765337-B2 Multilayer type electrophotographic photoconductor and image forming apparatus KYOCERA MITA CORPORATION (JP) 2014-07-01 — — US disclosed
US-8642236-B2 Electro photographic photoconductor and color image forming apparatus KYOCERA MITA CORPORATION (JP) 2014-02-04 — — US disclosed
CN-101713933-B A mono-layer electronic photographic photoreceptor with positive electricity and an image forming apparatus KYOCERA MITA CORP 2013-01-02 — — CN disclosed
EP-0747774-A2 Electrophotographic toner and contact development method using the toner MITA INDUSTRIAL CO., LTD. (JP) 1996-12-11 — — EP disclosed
EP-0738934-A2 Electrophotosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1996-10-23 — — EP disclosed
US-5548387-A IMAGE-FORMING APPARATUS MITA INDUSTRIAL CO., LTD. (JP) 1996-08-20 — — US disclosed
EP-0710892-A1 Electrophotosensitive material MITA INDUSTRIAL CO. LTD. (JP) 1996-05-08 — — EP disclosed
EP-0708377-A1 Toner for non-magnetic one-component development and method for contact type development using the same MITA INDUSTRIAL CO., LTD. (JP) 1996-04-24 — — EP disclosed
EP-0690354-A2 Method for contact type development MITA INDUSTRIAL CO., LTD. (JP) 1996-01-03 — — EP disclosed
US-5386279-A Electrostatics, electroconductive polyurethane, organic photosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1995-01-31 — — US disclosed
EP-0613067-A2 Transfer in an image-forming apparatus MITA INDUSTRIAL CO. LTD. (JP) 1994-08-31 — — EP disclosed
JP-S6361255-A ELECTROPHOTOGRAPHIC SENSITIVE BODY CANON INC 1988-03-17 — — JP disclosed
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