Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 11/20 | 0.33 |
| ▸ | SLC2A3 | P11169 | 11/20 | 0.33 |
| ▸ | SLC2A2 | P11168 | 9/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111646 | 0.87 | HTR1A (0.33) | SLC2A1SLC2A3SLC2A2DHFRHTR1A | |
| SCHEMBL113266 | 0.82 | DHFR (0.35) | MAPTSLC2A1SLC2A3SLC2A2LMNA | |
| SCHEMBL115724 | 0.82 | DHFR (0.33) | MAPTDHFRHTR1AHTR7 | |
| SCHEMBL113317 | 0.81 | DHFR (0.35) | DHFRHTR1AHTR7 | |
| SCHEMBL116207 | 0.80 | DHFR (0.33) | LMNADHFRHTR1AHTR7 | |
| SCHEMBL114932 | 0.80 | DHFR (0.35) | SLC2A1SLC2A3SLC2A2DHFRHTR1A | |
| SCHEMBL115607 | 0.78 | HTR1A (0.37) | MAPTLMNADHFRHTR1AHTR7 | |
| SCHEMBL116262 | 0.77 | CXCR3 (0.35) | DHFRHTR1AHTR7 | |
| SCHEMBL114668 | 0.77 | CXCR3 (0.41) | MAPTTP53LMNA | |
| SCHEMBL113412 | 0.77 | DHFR (0.35) | DHFRHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424840-A1 | CXCR3 RECEPTOR ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010126811-A1 | CXCR3 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-11-04 | — | — | WO | disclosed |