SCHEMBL22481201

SCHEMBL22481201

CC(C)(C)NC[C@H](O)c1cccc(Oc2ccccc2)n1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 6/20 0.56
CYP2D6 P10635 2/20 0.48
HIF1A Q16665 2/20 0.47
LMNA P02545 1/20 0.47
ADRB2 P07550 7/20 0.43
NFKB1 P19838 1/20 0.43
BLM P54132 1/20 0.42
ADRB3 P13945 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22481231 0.82 ADRB1 (0.60) ADRB1CYP2D6HIF1ALMNAADRB2
SCHEMBL22481127 0.82 ADRB1 (0.60) ADRB1CYP2D6HIF1ALMNAADRB2
SCHEMBL22481280 0.81 ADRB1 (0.59) ADRB1CYP2D6HIF1ALMNAADRB2
SCHEMBL22481325 0.81 ADRB1 (0.59) ADRB1CYP2D6HIF1ALMNAADRB2
SCHEMBL22480851 0.81 ADRB1 (0.59) ADRB1CYP2D6HIF1ALMNAADRB2
SCHEMBL22481191 0.81 ADRB1 (0.59) ADRB1CYP2D6HIF1ALMNAADRB2
SCHEMBL11467976 0.80 LMNA (0.42) LMNA
SCHEMBL22481132 0.80 ADRB1 (0.65) ADRB1CYP2D6HIF1ALMNAADRB2
SCHEMBL22480825 0.80 ADRB1 (0.65) ADRB1CYP2D6HIF1ALMNAADRB2
SCHEMBL24630880 0.76 ADRB1 (0.67) ADRB1CYP2D6HIF1ALMNAADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230263749-A1 COMPOSITIONS AND METHODS FOR IMPROVING NEUROLOGICAL DISEASES AND DISORDERS CURASEN THERAPEUTICS, INC. 2023-08-24 US disclosed
US-20230263749-A1 COMPOSITIONS AND METHODS FOR IMPROVING NEUROLOGICAL DISEASES AND DISORDERS CURASEN THERAPEUTICS, INC. 2023-08-24 US disclosed
US-20230157974-A1 COMPOSITIONS AND METHODS FOR IMPROVING NEUROLOGICAL DISEASES AND DISORDERS CURASEN THERAPEUTICS, INC. 2023-05-25 US disclosed
US-20230157974-A1 COMPOSITIONS AND METHODS FOR IMPROVING NEUROLOGICAL DISEASES AND DISORDERS CURASEN THERAPEUTICS, INC. 2023-05-25 US disclosed
US-20220169612-A1 BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME CURASEN THERAPEUTICS, INC. 2022-06-02 US disclosed
US-20210371380-A1 BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME CURASEN THERAPEUTICS, INC. 2021-12-02 US disclosed
US-11040944-B2 Beta adrenergic agonist and methods of using the same CURASEN THERAPEUTICS, INC. (US) 2021-06-22 US disclosed
US-10947196-B2 Beta adrenergic agonist and methods of using the same CURASEN THERAPEUTICS, INC. (US) 2021-03-16 US disclosed
US-20200308115-A1 BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME CURASEN THERAPEUTICS, INC. 2020-10-01 US disclosed
US-20200308114-A1 BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME CURASEN THERAPEUTICS, INC. 2020-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200308114-A1 BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME ADRB2, ADRB1, ADRA2C ADRB1 2/4885CYP2D6 946/4885HIF1A 2371/4885
US-20200308115-A1 BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME ADRB2, ADRB1, ADRA2C ADRB1 2/4885CYP2D6 946/4885HIF1A 2371/4885
US-10947196-B2 Beta adrenergic agonist and methods of using the same ADRB2, ADRB1, ADRA2C ADRB1 2/4885CYP2D6 946/4885HIF1A 2371/4885
US-20210371380-A1 BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME ADRB2, ADRB1, ADRA2C ADRB1 2/4885CYP2D6 946/4885HIF1A 2371/4885
US-11040944-B2 Beta adrenergic agonist and methods of using the same ADRB2, ADRB1, ADRA2C ADRB1 2/4885CYP2D6 946/4885HIF1A 2371/4885
US-20220169612-A1 BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME ADRA2B, ADRB2, ADRB1 ADRB1 3/4885CYP2D6 866/4885HIF1A 3024/4885
US-20230263749-A1 COMPOSITIONS AND METHODS FOR IMPROVING NEUROLOGICAL DISEASES AND DISORDERS ADRA2A, SNCA, ADRA1A ADRB1 5/4885CYP2D6 3407/4885HIF1A 701/4885
US-20230157974-A1 COMPOSITIONS AND METHODS FOR IMPROVING NEUROLOGICAL DISEASES AND DISORDERS ADRA2A, SNCA, ADRA1A ADRB1 5/4885CYP2D6 3407/4885HIF1A 701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.