Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11467983 | 0.81 | GAA (0.44) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL11483171 | 0.77 | RAB9A (0.49) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL11485886 | 0.76 | PTGES (0.47) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL11483085 | 0.76 | ACACB (0.47) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL11865062 | 0.76 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL11477369 | 0.76 | CACNA2D1 (0.45) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL11475908 | 0.74 | RAB9A (0.47) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL11469963 | 0.74 | GAA (0.48) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL11468314 | 0.74 | PTGES (0.45) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL11240195 | 0.73 | CACNA2D1 (0.49) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190725-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4021553-A | 5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1977-05-03 | — | — | US | disclosed |