Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1914807 | 0.94 | RAB9A (0.45) | MAPTRAB9ASMN1; SMN2NPC1STAT3 | |
| SCHEMBL1916734 | 0.87 | NISCH (0.39) | MAPTRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL17626120 | 0.76 | ALDH1A1 (0.45) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL11657350 | 0.75 | HSD17B10 (0.71) | MAPTRAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL11664281 | 0.75 | HSD17B10 (0.71) | MAPTRAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL11661972 | 0.75 | HSD17B10 (0.71) | MAPTRAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL11660215 | 0.75 | HSD17B10 (0.71) | MAPTRAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL1916781 | 0.74 | XDH (0.41) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL19938080 | 0.73 | KMT2A (0.54) | MAPTRAB9ASMN1; SMN2NPC1STAT3 | |
| SCHEMBL31549867 | 0.73 | RARB (0.68) | MAPTRAB9ASMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4201779-A | 7[(2-Amino-thiazol-4-yl)glyoxylamido]-cephem derivatives and processes for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-05-06 | — | — | US | disclosed |
| US-4016159-A | BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |