SCHEMBL11468281

SCHEMBL11468281

CCC(C)(CC)CC(=O)CBr

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.35
ALDH1A1 P00352 1/20 0.32
FAAH O00519 2/20 0.31
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11477036 0.80 TRPA1 (0.35) TRPA1ALDH1A1FAAHTSHRTDP1
SCHEMBL841626 0.76
SCHEMBL11474674 0.75 TDP1 (0.30) TDP1
SCHEMBL11459463 0.75 FAAH (0.31) FAAHTSHRTDP1
SCHEMBL11724430 0.74
SCHEMBL17129998 0.74 TDP1 (0.47) ALDH1A1TSHRTDP1
SCHEMBL17933420 0.70 ALDH1A1 (0.42) TRPA1ALDH1A1TSHRTDP1
SCHEMBL27647738 0.70 TSHR (0.41) ALDH1A1TSHRTDP1
SCHEMBL1419066 0.70 HMGCR (0.52) ALDH1A1TSHRTDP1
SCHEMBL13623133 0.70 TRPA1 (0.41) TRPA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4240983-A HALOGENATION BAYER AKTIENGESELLSCHAFT (DE) 1980-12-23 US disclosed