Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27921550 | 0.86 | KMT2A (0.60) | KMT2ASMN1; SMN2MEN1TSHRMAPK1 | |
| SCHEMBL14690465 | 0.78 | KMT2A (0.56) | KMT2ASMN1; SMN2MEN1TSHRMAPK1 | |
| SCHEMBL14646837 | 0.78 | KMT2A (0.56) | KMT2ASMN1; SMN2MEN1TSHRMAPK1 | |
| SCHEMBL8148063 | 0.77 | MEN1 (0.61) | KMT2ASMN1; SMN2MEN1TSHRMAPT | |
| Methyl Syringate SCHEMBL211747 | 0.77 | MEN1 (0.61) | KMT2ASMN1; SMN2MEN1TSHRMAPK1 | |
| SCHEMBL27945770 | 0.77 | KMT2A (0.52) | KMT2ASMN1; SMN2MEN1TSHRMAPK1 | |
| Chloroform SCHEMBL7815652 | 0.77 | LMNA (0.60) | KMT2AMEN1MAPK1PDK1ALDH1A1 | |
| SCHEMBL7123362 | 0.77 | MEN1 (0.56) | KMT2ASMN1; SMN2MEN1TSHRMAPT | |
| SCHEMBL669351 | 0.76 | MEN1 (0.59) | KMT2ASMN1; SMN2MEN1TSHRMAPT | |
| SCHEMBL7960025 | 0.76 | MEN1 (0.59) | KMT2ASMN1; SMN2MEN1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198416-A | 5-Alkoxy-picolinic esters and anti-hypertensive composition containing 5-alkoxy-picolinic esters | MEIJI SEIKA KAISHA, LTD. (JP) | 1980-04-15 | — | — | US | disclosed |
| US-4189489-A | 5-Alkoxy-picolinic acid calcium salts and anti-hypertensive composition containing 5-alkoxy-picolinic acid calcium salts and anti-hypertensive composition thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 1980-02-19 | — | — | US | disclosed |