Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14402423 | 0.85 | AOC3 (0.60) | AOC3L3MBTL1SLC6A2SLC6A4MTNR1A | |
| SCHEMBL9392741 | 0.83 | MTNR1A (0.58) | AOC3L3MBTL1ROCK2ROCK1MTNR1A | |
| SCHEMBL11174933 | 0.81 | AOC3 (0.50) | AOC3L3MBTL1ROCK2ROCK1MTNR1A | |
| SCHEMBL6490320 | 0.81 | AOC3 (0.62) | AOC3L3MBTL1ROCK2ROCK1MTNR1A | |
| SCHEMBL28538450 | 0.81 | AOC3 (0.49) | AOC3L3MBTL1SLC6A2SLC6A4ROCK2 | |
| SCHEMBL24527630 | 0.80 | AOC3 (0.53) | AOC3L3MBTL1ROCK2ROCK1MTNR1A | |
| SCHEMBL6301269 | 0.80 | MTNR1A (0.63) | AOC3L3MBTL1ROCK2ROCK1MTNR1A | |
| SCHEMBL382558 | 0.80 | AOC3 (0.53) | AOC3L3MBTL1ROCK2ROCK1MTNR1A | |
| SCHEMBL19217778 | 0.79 | AOC3 (0.62) | AOC3L3MBTL1SLC6A2SLC6A4TSHR | |
| SCHEMBL4032416 | 0.79 | AOC3 (0.67) | AOC3L3MBTL1ROCK2ROCK1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4186142-A | Cyclization substrates and 6α-substituted 19-norsteroid derivatives | AKZONA INCORPORATED (US) | 1980-01-29 | — | — | US | disclosed |