Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.63 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.63 |
| ▸ | CASR | P41180 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9392741 | 0.97 | MTNR1A (0.58) | MTNR1AMTNR1BCASRMEN1KMT2A | |
| SCHEMBL17295959 | 0.86 | MTNR1A (0.58) | MTNR1AMTNR1BCASRMEN1KMT2A | |
| SCHEMBL9658024 | 0.85 | MTNR1A (0.49) | MTNR1AMTNR1BCASRMEN1KMT2A | |
| SCHEMBL7857706 | 0.83 | HRH1 (0.60) | MTNR1AMTNR1BCASRMEN1KMT2A | |
| SCHEMBL6302107 | 0.83 | MTNR1A (0.59) | MTNR1AMTNR1BCASRMEN1KMT2A | |
| SCHEMBL6301200 | 0.83 | MTNR1A (0.67) | MTNR1AMTNR1BCASRMEN1KMT2A | |
| SCHEMBL8661020 | 0.82 | AOC3 (0.54) | MTNR1AMTNR1BCASRLMNAAOC3 | |
| SCHEMBL6490320 | 0.81 | AOC3 (0.62) | MTNR1AMTNR1BAOC3L3MBTL1ROCK2 | |
| SCHEMBL11174933 | 0.81 | AOC3 (0.50) | MTNR1AMTNR1BCASRAOC3L3MBTL1 | |
| SCHEMBL6774246 | 0.81 | OPRD1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1310924-C | Chiral copper complex and production processes thereof and using the same | SUMITOMO CHEMICAL CO (JP) | 2007-04-18 | — | — | CN | disclosed |
| CN-1246299-C | Chiral copper complex, preparation method and application thereof | SUMITOMO CHEMICAL CO (JP) | 2006-03-22 | — | — | CN | disclosed |
| US-6943183-B2 | 5-substituted tetralones as inhibitors of ras farnesyl transferase | PFIZER INC (US) | 2005-09-13 | — | — | US | disclosed |
| CN-1616465-A | Chiral copper complex and production processes thereof and using the same | SUMITOMO CHEMICAL CO (JP) | 2005-05-18 | — | — | CN | disclosed |
| CN-1182915-C | Chiral copper complex catalyst composition and method for asymmetrical preparation | ס�ѻ�ѧ��ҵ��ʽ���� | 2005-01-05 | — | — | CN | disclosed |
| US-20040044057-A1 | 5- substituted tetralones as inhibitors of ras farnesyl trransferase | WARNER-LAMBERT COMPANY | 2004-03-04 | — | — | US | disclosed |
| EP-1276725-A2 | 5-SUBSTITUTED TETRALONES AS INHIBITORS OF RAS FARNESYL TRANSFERASE | WARNER-LAMBERT COMPANY (US) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001079180-A2 | 5-SUBSTITUTED TETRALONES AS INHIBITORS OF RAS FARNESYL TRANSFERASE | WARNER-LAMBERT COMPANY (US) | 2001-10-25 | — | — | WO | disclosed |
| CN-1314209-A | Chiral copper complex catalyst composition and method for asymmetrical preparation | SUMITOMO CHEMICAL CO (JP) | 2001-09-26 | — | — | CN | disclosed |
| CN-1313277-A | Chiral copper complex, preparation method and application thereof | SUMITOMO CHEMICAL CO (JP) | 2001-09-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044057-A1 | 5- substituted tetralones as inhibitors of ras farnesyl trransferase | PTAR1, FNTA, GGPS1 | MTNR1A 2828/4885MTNR1B 3212/4885CASR 2450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.