Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295108 | 0.82 | AOC3 (0.48) | AOC3 | |
| SCHEMBL19217778 | 0.82 | AOC3 (0.62) | AOC3L3MBTL1TAAR1CASRIDO1 | |
| SCHEMBL11081355 | 0.81 | AOC3 (0.54) | AOC3L3MBTL1TAAR1ALDH1A1CYP3A4 | |
| SCHEMBL14655677 | 0.81 | ALDH1A1 (0.46) | AOC3L3MBTL1TAAR1ALDH1A1CYP3A4 | |
| SCHEMBL14402423 | 0.81 | AOC3 (0.60) | AOC3L3MBTL1CASR | |
| SCHEMBL6744940 | 0.80 | AOC3 (1.00) | AOC3L3MBTL1 | |
| SCHEMBL10860910 | 0.80 | AOC3 (0.66) | AOC3TAAR1IDO1 | |
| SCHEMBL413321 | 0.80 | TAAR1 (0.53) | AOC3L3MBTL1TAAR1ALDH1A1CYP3A4 | |
| SCHEMBL410128 | 0.80 | TAAR1 (0.53) | AOC3L3MBTL1TAAR1ALDH1A1CYP3A4 | |
| SCHEMBL1473114 | 0.80 | AOC3 (0.53) | AOC3L3MBTL1TAAR1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109887681-A | Preparation method of high-conductivity heat-resistant aluminum alloy conductor | 广西纵览线缆集团有限公司 | 2019-06-14 | — | — | CN | claimed |
| CN-104130257-A | One-dimensional organic semiconductor spiral nano-wires with fluorescence response upon organic amine gases, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2014-11-05 | — | — | CN | claimed |
| CN-101781256-B | Method for preparing 4-methyl-2-propyl-1H-benzimidazole-6-formamide compound | BEIJING INSTITUTE OF TECHNOLOGY (CN) | 2011-12-07 | — | — | CN | claimed |
| CN-101781256-A | Method for preparing 4-methyl-2-propyl-1H-benzimidazole-6-formamide compound | BEIJING INST TECHNOLOGY | 2010-07-21 | — | — | CN | claimed |
| EP-3483149-B1 | BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | YUHAN CORP (KR) | 2021-01-13 | — | — | EP | disclosed |
| US-10383859-B2 | Benzo[d]thiazole derivative or salt thereof, and pharmaceutical composition including same | YUHAN CORPORATION (KR) | 2019-08-20 | — | — | US | disclosed |
| CN-109887681-A | Preparation method of high-conductivity heat-resistant aluminum alloy conductor | 广西纵览线缆集团有限公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-109859894-A | High-strength aluminum alloy conductor for overhead transmission line | 广西纵览线缆集团有限公司 | 2019-06-07 | — | — | CN | disclosed |
| CN-109859894-A | High-strength aluminum alloy conductor for overhead transmission line | 广西纵览线缆集团有限公司 | 2019-06-07 | — | — | CN | disclosed |
| US-20190142809-A1 | Benzo[D]Thiazole Derivative Or Salt Thereof, And Pharmaceutical Composition Including Same | YUHAN CORPORATION (KR) | 2019-05-16 | — | — | US | disclosed |
| EP-3483149-A1 | BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Yuhan Corporation (KR) | 2019-05-15 | — | — | EP | disclosed |
| CN-104130257-B | One-dimensional organic semiconductor spiral nano-wires with fluorescence response upon organic amine gases, and preparation method and application thereof | 中国科学院化学研究所 | 2017-02-15 | — | — | CN | disclosed |
| US-20030176415-A1 | 1,2,3,4-tetrahydroisoquinoline derivatives | IDORSIA PHARMACEUTICALS LTD (CH) | 2003-09-18 | — | — | US | disclosed |
| US-20030069239-A1 | Substituted 2-aryl-4-arylaminopyrimidines and analogs as activators or caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2003-04-10 | — | — | US | disclosed |
| EP-1274687-A1 | 1,2,3,4- TETRAHYDROISOQUINOLINE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2003-01-15 | — | — | EP | disclosed |
| WO-2002047690-A1 | SUBSTITUTED 2-ARYL-4-ARYLAMINOPYRIMIDINES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2002-06-20 | — | — | WO | disclosed |
| WO-2001068609-A1 | 1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD. (CH) | 2001-09-20 | — | — | WO | disclosed |
| WO-1999064861-A2 | METHOD OF IDENTIFYING ANTIDEPRESSANT COMPOUNDS | UNIVERSITY COLLEGE LONDON (GB) | 1999-12-16 | — | — | WO | disclosed |
| CN-1069882-A | The Compounds and methods for that suppresses HIV and correlated virus | MEDIVIR AB (CH) | 1993-03-17 | — | — | CN | disclosed |
| US-4191765-A | 1-Aryloxy-2-hydroxy-3-aminopropanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190142809-A1 | Benzo[D]Thiazole Derivative Or Salt Thereof, And Pharmaceutical Composition Including Same | ILK, SBDS, BDKRB1 | AOC3 4800/4885L3MBTL1 1733/4885TAAR1 3745/4885 |
| US-10383859-B2 | Benzo[d]thiazole derivative or salt thereof, and pharmaceutical composition including same | ILK, SBDS, BDKRB1 | AOC3 4800/4885L3MBTL1 1733/4885TAAR1 3745/4885 |
| US-20030176415-A1 | 1,2,3,4-tetrahydroisoquinoline derivatives | HCRTR2, HCRTR1, NPY2R | AOC3 545/4885L3MBTL1 4869/4885TAAR1 128/4885 |
| US-20030069239-A1 | Substituted 2-aryl-4-arylaminopyrimidines and analogs as activators or caspases and inducers of apoptosis and the use thereof | API5, CASP2, APAF1 | AOC3 2480/4885L3MBTL1 746/4885TAAR1 3971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.