Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374418 | 0.84 | NPSR1 (0.41) | RAB9APOLBGAASMN1; SMN2CHRM3 | |
| SCHEMBL826276 | 0.84 | CHRM3 (0.49) | RAB9APOLBGAASMN1; SMN2CHRM3 | |
| SCHEMBL2654268 | 0.84 | ALDH1A1 (0.41) | RAB9APOLBGAASMN1; SMN2CHRM3 | |
| SCHEMBL4636677 | 0.84 | CHRM3 (0.48) | RAB9APOLBGAASMN1; SMN2CHRM3 | |
| SCHEMBL2130216 | 0.81 | PIN1 (0.44) | POLBGAASMN1; SMN2CHRM3CHRM2 | |
| SCHEMBL27740728 | 0.81 | MMP1 (0.40) | POLBGAASMN1; SMN2CHRM3CHRM2 | |
| SCHEMBL11881887 | 0.79 | ALDH1A1 (0.39) | RAB9APOLBGAASMN1; SMN2CHRM3 | |
| SCHEMBL1827117 | 0.79 | DAO (0.42) | SMN1; SMN2CHRM3CHRM2CHRM1TSHR | |
| SCHEMBL7371709 | 0.79 | KCNN4 (0.41) | RAB9APOLBGAASMN1; SMN2CHRM3 | |
| SCHEMBL28025273 | 0.79 | CHRM3 (0.51) | RAB9APOLBGAASMN1; SMN2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4208423-A | Anticholinergic bronchodilators | SYNTEX INC. (US) | 1980-06-17 | — | — | US | disclosed |
| EP-0012071-A1 | Azoniaspiro derivatives, process for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1980-06-11 | — | — | EP | disclosed |