Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 13/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11476188 | 0.88 | ADRB3 (0.58) | ADRB2ADRB3ADRB1CYP2D6ADRA1A | |
| SCHEMBL11507196 | 0.86 | ADRB2 (0.66) | ADRB2ADRB3ADRB1CYP2D6ADRA1A | |
| SCHEMBL11465951 | 0.81 | ADRB3 (0.54) | ADRB2ADRB3ADRB1CYP2D6ADRA1A | |
| SCHEMBL11509194 | 0.80 | ADRB2 (0.57) | ADRB2ADRB1CYP2D6ADRA1ANR3C1 | |
| SCHEMBL11522642 | 0.76 | ADRB3 (0.70) | ADRB2ADRB3ADRB1CYP2D6ADRA1A | |
| SCHEMBL11310357 | 0.75 | ADRB2 (1.00) | ADRB2ADRB3ADRB1CYP2D6ADRA1A | |
| SCHEMBL11506652 | 0.74 | ADRB2 (0.65) | ADRB2ADRB1CYP2D6ADRA1ANR3C1 | |
| SCHEMBL11522665 | 0.74 | ADRB3 (0.69) | ADRB2ADRB3ADRB1CYP2D6CYP3A4 | |
| SCHEMBL2615170 | 0.73 | ADRB2 (0.66) | ADRB2ADRB3ADRB1CYP2D6ADRA1A | |
| SCHEMBL11506733 | 0.73 | ADRB2 (0.66) | ADRB2ADRB3ADRB1CYP2D6ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011295-A1 | Yellow monoazo dyes of the 2-hydroxydibenzofuran series; their preparation and use for dyeing and printing synthetic hydrophobic fibres | Montedison S.p.A. (IT) | 1980-05-28 | — | — | EP | disclosed |
| EP-0007294-A2 | Membrane stabilizing compounds having beta-receptor blocking activity, their preparation, method for treatment of arrhythmic conditions, and pharmaceutical preparations containing same | Aktiebolaget Hässle (SE) | 1980-01-23 | — | — | EP | disclosed |