Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | AHR | P35869 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | PNLIP | P16233 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472247 | 0.84 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AKCNMA1MAPT | |
| SCHEMBL30692656 | 0.84 | MEN1 (0.81) | ALDH1A1MEN1KMT2AKCNMA1MAPT | |
| SCHEMBL11466437 | 0.84 | MEN1 (0.81) | ALDH1A1MEN1KMT2AKCNMA1MAPT | |
| SCHEMBL8316833 | 0.84 | SMN1; SMN2 (0.61) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL7341264 | 0.83 | TSHR (0.68) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL24438298 | 0.83 | PNLIP (0.79) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL30692674 | 0.83 | PNLIP (0.79) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL11462804 | 0.83 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AKCNMA1MAPT | |
| SCHEMBL29655258 | 0.82 | PNLIP (0.83) | ALDH1A1MEN1KMT2AHTTPNLIP | |
| SCHEMBL24438029 | 0.82 | PNLIP (0.83) | ALDH1A1MEN1KMT2AHTTPNLIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4221815-A | HYPOGLYCEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-09-09 | — | — | US | disclosed |