Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | JAK2 | O60674 | 3/20 | 0.60 |
| ▸ | JAK1 | P23458 | 3/20 | 0.60 |
| ▸ | TYK2 | P29597 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341264 | 0.91 | TSHR (0.68) | SMN1; SMN2JAK2JAK1TYK2TSHR | |
| SCHEMBL11775702 | 0.87 | ALDH1A1 (0.58) | SMN1; SMN2PKMRXFP1JAK2JAK1 | |
| SCHEMBL29929613 | 0.85 | JAK2 (0.78) | SMN1; SMN2PKMRXFP1JAK2JAK1 | |
| SCHEMBL11468587 | 0.84 | ALDH1A1 (0.68) | SMN1; SMN2ALDH1A1TP53TSHRLMNA | |
| SCHEMBL20601659 | 0.83 | HDAC8 (0.67) | SMN1; SMN2PKMRXFP1JAK2JAK1 | |
| SCHEMBL4253890 | 0.83 | MEN1 (0.68) | PKMJAK2JAK1TYK2LMNA | |
| SCHEMBL12700230 | 0.81 | ALDH1A1 (0.64) | SMN1; SMN2PKMALDH1A1NPC1RAB9A | |
| SCHEMBL10612716 | 0.81 | TMPRSS4 (0.73) | SMN1; SMN2PKMRXFP1JAK2JAK1 | |
| SCHEMBL11575433 | 0.80 | ALDH1A1 (0.63) | SMN1; SMN2PKMRXFP1JAK2JAK1 | |
| SCHEMBL6005591 | 0.80 | JAK2 (0.69) | SMN1; SMN2PKMRXFP1JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |