Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | LOX | P28300 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531653 | 0.84 | MEN1 (0.72) | KMT2AMEN1EPHX2ALDH1A1POLB | |
| SCHEMBL2920100 | 0.84 | MEN1 (0.72) | KMT2AMEN1EPHX2CA1CA2 | |
| SCHEMBL3517085 | 0.84 | KMT2A (0.72) | KMT2AMEN1EPHX2MAPTNPSR1 | |
| SCHEMBL1939359 | 0.84 | KMT2A (0.72) | KMT2AMEN1EPHX2MAPTNPSR1 | |
| SCHEMBL11535141 | 0.84 | MEN1 (0.72) | KMT2AMEN1EPHX2MAPTNPSR1 | |
| SCHEMBL56319 | 0.84 | LOX (0.57) | KMT2AMEN1LOXHRH3GAA | |
| SCHEMBL12015818 | 0.84 | KMT2A (0.67) | KMT2AMEN1EPHX2MAPTNPSR1 | |
| SCHEMBL7798812 | 0.83 | LMNA (0.51) | KMT2AMEN1CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL11529235 | 0.83 | KMT2A (0.97) | KMT2AMEN1EPHX2MAPTNPSR1 | |
| SCHEMBL13408045 | 0.82 | MEN1 (0.69) | KMT2AMEN1EPHX2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133132-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-05-04 | — | — | US | disclosed |
| EP-1272477-B1 | PYRIMIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2007-05-09 | — | — | EP | disclosed |
| US-7153964-B2 | Pyrimidine compounds | ASTRAZENECA AB (SE) | 2006-12-26 | — | — | US | disclosed |
| US-20030149064-A1 | Pyrimidine compounds | ASTRAZENECA AB (SE) | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133132-A1 | NAMPT MODULATORS | NAMPT, MC4R, SIRT1 | KMT2A 1669/4885MEN1 484/4885EPHX2 4344/4885 |
| US-20030149064-A1 | Pyrimidine compounds | CDK2, CCNI, CCNY | KMT2A 227/4885MEN1 3100/4885EPHX2 1134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.