Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11450839 | 0.87 | LMNA (0.40) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL14839262 | 0.81 | TSHR (0.45) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11459385 | 0.78 | TSHR (0.33) | MAPTALDH1A1SMN1; SMN2TSHRGAA | |
| SCHEMBL11468691 | 0.76 | POLB (0.37) | MEN1KMT2AMAPTALDH1A1F2 | |
| SCHEMBL11449565 | 0.75 | LMNA (0.38) | KMT2AMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL11468754 | 0.75 | HRH3 (0.43) | MAPTALDH1A1HPGDPOLBTSHR | |
| SCHEMBL11202373 | 0.74 | TSHR (0.32) | TSHR | |
| SCHEMBL14839400 | 0.74 | TSHR (0.45) | MEN1KMT2AALDH1A1MAPK1POLB | |
| SCHEMBL11458868 | 0.73 | GAA (0.42) | MEN1KMT2AALDH1A1MAPK1NPSR1 | |
| SCHEMBL13242262 | 0.73 | PRKCA (0.40) | ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4212974-A | POLYMER STABILIZERS | SANKYO COMPANY LIMITED (JP) | 1980-07-15 | — | — | US | disclosed |