Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11450306 | 0.87 | NPC1 (0.48) | POLBNPC1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL11467404 | 0.85 | GAA (0.39) | POLBHTR7NPC1CHRNB2CHRNA7 | |
| SCHEMBL11449160 | 0.81 | HTR7 (0.34) | POLBHTR7NPC1MEN1KMT2A | |
| SCHEMBL4983482 | 0.80 | HTR7 (0.37) | POLBHTR7NPC1CHRNB2CHRNA7 | |
| SCHEMBL11449337 | 0.78 | PDK1 (0.35) | ALDH1A1 | |
| SCHEMBL11467326 | 0.78 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL11449793 | 0.77 | NPC1 (0.45) | POLBNPC1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL25702381 | 0.76 | HTR7 (0.36) | POLBHTR7NPC1CHRNB2CHRNA7 | |
| SCHEMBL11468678 | 0.76 | MEN1 (0.37) | POLBBCHEMEN1KMT2AALDH1A1 | |
| SCHEMBL3240666 | 0.75 | MAPT (0.45) | POLBMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4212974-A | POLYMER STABILIZERS | SANKYO COMPANY LIMITED (JP) | 1980-07-15 | — | — | US | disclosed |