Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557815 | 0.89 | HDAC4 (0.41) | HDAC4HDAC7HDAC5CES2CES1 | |
| Hexane SCHEMBL11469486 | 0.83 | ALDH1A1 (0.44) | MAPTOPRL1OPRM1OPRD1OPRK1 | |
| Hexane SCHEMBL11478445 | 0.82 | LMNA (0.38) | — | |
| Hexane SCHEMBL11479643 | 0.74 | ALDH1A1 (0.36) | AOC3OPRL1OPRM1OPRK1 | |
| SCHEMBL8084012 | 0.73 | HDAC4 (0.38) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL2554823 | 0.73 | ALDH1A1 (0.43) | AOC3 | |
| SCHEMBL11468775 | 0.73 | CES2 (0.40) | MAPTHDAC4HDAC7HDAC5CES2 | |
| SCHEMBL27907592 | 0.71 | HDAC4 (0.39) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL4169139 | 0.70 | ACP3 (0.40) | MAPTAOC3 | |
| SCHEMBL954467 | 0.70 | AOC3 (0.40) | MAPTHDAC4HDAC7HDAC5CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4209621-A | TRANQUILIZERS | AMERICAN CYANAMID COMPANY (US) | 1980-06-24 | — | — | US | disclosed |