Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646517 | 0.85 | TSHR (0.34) | TSHRDNM1FAAHTRPV1ADH1B | |
| SCHEMBL8764482 | 0.83 | TSHR (0.38) | TSHRDNM1FAAHTRPV1ADH1B | |
| SCHEMBL10897612 | 0.81 | ADH1B (0.39) | TSHRDNM1FAAHTRPV1ADH1B | |
| SCHEMBL8735086 | 0.81 | ADH1B (0.39) | TSHRDNM1FAAHTRPV1ADH1B | |
| SCHEMBL7176175 | 0.78 | TSHR (0.41) | TSHRDNM1FAAHTRPV1ADH1B | |
| SCHEMBL9645620 | 0.78 | TSHR (0.33) | TSHRALDH1A1 | |
| Heptane SCHEMBL17076906 | 0.77 | TSHR (0.44) | TSHRDNM1THRBALDH1A1 | |
| SCHEMBL6065522 | 0.77 | TSHR (0.44) | TSHRDNM1THRBALDH1A1 | |
| Heptane SCHEMBL17076924 | 0.77 | TSHR (0.44) | TSHRDNM1THRBALDH1A1 | |
| SCHEMBL27917257 | 0.77 | TSHR (0.44) | TSHRDNM1THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200545-A | Amino phenol-detergent/dispersant combinations and fuels and lubricants containing same | THE LUBRIZOL CORPORATION (US) | 1980-04-29 | — | — | US | disclosed |