Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917257 | 1.00 | TSHR (0.44) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL4894065 | 1.00 | TSHR (0.44) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL3156871 | 1.00 | TSHR (0.44) | TSHRTHRBLMNADNM1OPRM1 | |
| Heptane SCHEMBL17076924 | 1.00 | TSHR (0.44) | TSHRTHRBLMNADNM1OPRM1 | |
| Heptane SCHEMBL17076872 | 1.00 | TSHR (0.44) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL15189290 | 1.00 | TSHR (0.44) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL6065522 | 1.00 | TSHR (0.44) | TSHRTHRBLMNADNM1OPRM1 | |
| Phosphine SCHEMBL19411938 | 0.97 | LMNA (0.42) | TSHRTHRBLMNADNM1OPRM1 | |
| Ammonia Solution, Strong SCHEMBL7229632 | 0.97 | LMNA (0.42) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL3602893 | 0.97 | OPRM1 (0.43) | TSHRTHRBLMNADNM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926765-B | 4, 6-difluorodibenzofuran derivatives | 默克专利股份有限公司 | 2021-11-30 | — | — | CN | disclosed |
| US-20210284911-A1 | Electro-Optical Display Elements | MERCK PATENT GMBH (DE) | 2021-09-16 | — | — | US | disclosed |
| US-20180030020-A1 | 4,6-DIFLUORODIBENZOFURAN DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-02-01 | — | — | US | disclosed |
| US-20150259602-A1 | 4,6-DIFLUORODIBENZOFURAN DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180030020-A1 | 4,6-DIFLUORODIBENZOFURAN DERIVATIVES | CYP4F2, CYP2F1, NEFM | TSHR 2340/4885THRB 2334/4885LMNA 2322/4885 |
| US-20210284911-A1 | Electro-Optical Display Elements | VCL, CASK, SDF4 | TSHR 3283/4885THRB 3791/4885LMNA 3469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.