Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4346868 | 0.90 | ALOX5 (0.42) | ALOX5ALDH1A1TSHRTHRBEPHX1 | |
| SCHEMBL19691908 | 0.87 | ALOX5 (0.55) | ALOX5ALDH1A1TSHRTHRBEPHX1 | |
| SCHEMBL1476715 | 0.87 | ALOX5 (0.55) | ALOX5ALDH1A1TSHRTHRBEPHX1 | |
| SCHEMBL1611049 | 0.87 | ALOX5 (0.55) | ALOX5ALDH1A1TSHRTHRBEPHX1 | |
| SCHEMBL1476747 | 0.87 | ALOX5 (0.55) | ALOX5ALDH1A1TSHRTHRBEPHX1 | |
| SCHEMBL19692314 | 0.87 | ALOX5 (0.55) | ALOX5ALDH1A1TSHRTHRBEPHX1 | |
| SCHEMBL2961154 | 0.82 | ALOX5 (0.50) | ALOX5ALDH1A1TSHRTHRBEPHX1 | |
| SCHEMBL2966938 | 0.82 | ALOX5 (0.50) | ALOX5ALDH1A1TSHRTHRBEPHX1 | |
| SCHEMBL31453497 | 0.80 | ALOX5 (0.61) | ALOX5ALDH1A1TSHRTHRBEPHX1 | |
| SCHEMBL31453498 | 0.77 | ALOX5 (0.57) | ALOX5ALDH1A1TSHRTHRBEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4197379-A | RUBBER COMPRISING COPOLYMER OF BUTADIENE OR ISOPRENE AND VINYL NITRILE, REACTED WITH DIMETHYLOL PHENOLIC COMPOUND | MONSANTO COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
| US-4173556-A | Elastoplastic compositions of rubber and polyamide | MONSANTO COMPANY (US) | 1979-11-06 | — | — | US | disclosed |