Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11479612 | 0.84 | LMNA (0.53) | LMNAADORA3BRD4APOBEC3AAPOBEC3G | |
| SCHEMBL11662844 | 0.82 | LMNA (0.47) | LMNAADORA3BRD4GAA | |
| SCHEMBL11159584 | 0.81 | LMNA (0.53) | LMNAADORA3BRD4APOBEC3AAPOBEC3G | |
| SCHEMBL11471244 | 0.77 | LMNA (0.53) | LMNAADORA3BRD4APOBEC3AAPOBEC3G | |
| SCHEMBL11478019 | 0.75 | LMNA (0.48) | LMNAADORA3BRD4APOBEC3AAPOBEC3G | |
| SCHEMBL11481275 | 0.74 | LMNA (0.53) | LMNAADORA3APOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL11818528 | 0.74 | LMNA (0.45) | LMNAADORA3BRD4APOBEC3AAPOBEC3G | |
| SCHEMBL11822093 | 0.74 | LMNA (0.45) | LMNAADORA3BRD4APOBEC3AAPOBEC3G | |
| SCHEMBL11472434 | 0.74 | LMNA (0.44) | LMNAADORA3ALDH1A1GAATDP1 | |
| SCHEMBL11468352 | 0.70 | LMNA (0.41) | LMNAADORA3BRD4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202974-A | Process for preparing 3,4-dihydro-2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-13 | — | — | US | disclosed |