Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 8/20 | 0.55 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11158937 | 0.94 | CASR (0.57) | CASRGRIK2LMNATP53MAPT | |
| SCHEMBL11160051 | 0.89 | CASR (0.59) | CASRGRIK2LMNATP53MAPT | |
| SCHEMBL11164228 | 0.87 | CASR (0.57) | CASRGRIK2LMNATP53MAPT | |
| SCHEMBL11462576 | 0.85 | CASR (0.59) | CASRGRIK2LMNATP53MAPT | |
| SCHEMBL11460792 | 0.81 | CASR (0.62) | CASRGRIK2LMNATP53MAPT | |
| SCHEMBL11468901 | 0.81 | CASR (0.51) | CASRLMNATP53MAPTPTGDR2 | |
| SCHEMBL11462815 | 0.79 | NR1I2 (0.48) | LMNATP53MAPTKDM4EALDH1A1 | |
| Ciproquazone SCHEMBL287449 | 0.78 | CASR (0.58) | CASRGRIK2LMNATP53MAPT | |
| SCHEMBL11468011 | 0.77 | MAPT (0.56) | LMNATP53MAPTKDM4ENPSR1 | |
| SCHEMBL11167234 | 0.76 | CASR (0.48) | CASRGRIK2MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202895-A | 1-Polyhaloalkyl-2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-13 | — | — | US | disclosed |