Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 5/20 | 0.39 |
| ▸ | FNTB | P49356 | 5/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11480362 | 0.83 | ALDH1A1 (0.41) | POLBHSP90AA1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL11472531 | 0.83 | FNTA (0.42) | FNTAFNTBPGGT1BHSP90AA1CYP11B1 | |
| SCHEMBL21421 | 0.82 | CYP11B1 (0.52) | POLBHSP90AA1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL11469917 | 0.78 | HSP90AA1 (0.39) | POLBFNTAFNTBPGGT1BHSP90AA1 | |
| SCHEMBL11242742 | 0.76 | OGG1 (0.47) | FNTAFNTBPGGT1BHSP90AA1CYP11B1 | |
| SCHEMBL9804757 | 0.76 | TLR7 (0.36) | L3MBTL1KDM4E | |
| SCHEMBL11352932 | 0.76 | POLB (0.45) | POLBFNTAFNTBHSP90AA1CYP11B1 | |
| SCHEMBL11348607 | 0.76 | POLB (0.45) | POLBFNTAFNTBHSP90AA1CYP11B1 | |
| SCHEMBL11354100 | 0.75 | HSP90AA1 (0.42) | POLBHSP90AA1CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL11472555 | 0.75 | OGG1 (0.47) | FNTAFNTBPGGT1BHSP90AA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225723-A | Process for the preparation of substituted arylcyanoalkyl and diaryl cyanoalkylimidazoles | ROHM AND HAAS COMPANY (US) | 1980-09-30 | — | — | US | disclosed |
| US-4143137-A | SUBSTITUTED ARYLCYANOALKYL AND DIARYLCYANOALKYLIMIDAZOLE METAL SALT COMPLEXES AND FUNGICIDAL COMPOSITIONS AND METHODS UTILIZING THEM | ROHM AND HAAS COMPANY (US) | 1979-03-06 | — | — | US | disclosed |