Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | LDHB | P07195 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472667 | 0.87 | TDP1 (0.41) | RCE1LDHALDHBKDM4ENPC1 | |
| SCHEMBL11153688 | 0.85 | PGR (0.44) | LDHALDHBDAPK3ROCK2CHEK2 | |
| SCHEMBL3343884 | 0.85 | DAPK3 (0.50) | DAPK3ROCK2CHEK2PIM1PLK1 | |
| Hydrochloric Acid SCHEMBL11155377 | 0.83 | DAPK3 (0.40) | LDHALDHBDAPK3ROCK2CHEK2 | |
| SCHEMBL11153637 | 0.83 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2HPGDEPHX1 | |
| SCHEMBL11155671 | 0.81 | USP5 (0.50) | RAB9ASMN1; SMN2 | |
| SCHEMBL11156920 | 0.81 | NPC1 (0.40) | LDHALDHBDAPK3ROCK2CHEK2 | |
| SCHEMBL11155037 | 0.80 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2HPGDEPHX1 | |
| SCHEMBL11462135 | 0.80 | PGR (0.47) | RCE1SRD5A2NPC1RAB9AEPHX1 | |
| Benzene SCHEMBL11502999 | 0.79 | EPHX2 (0.38) | RCE1LDHALDHBDAPK3ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4227014-A | ANTILIPEMIC AGENTS, ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-10-07 | — | — | US | claimed |