SCHEMBL3343884

SCHEMBL3343884

CC(Nc1ccc(NC(C)C2CCCCC2)cc1)C1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAPK3 O43293 1/20 0.50
ROCK2 O75116 1/20 0.50
CHEK2 O96017 1/20 0.50
PIM1 P11309 1/20 0.50
PLK1 P53350 1/20 0.50
ROCK1 Q13464 1/20 0.50
CDC42BPA Q5VT25 1/20 0.50
AURKB Q96GD4 1/20 0.50
PLK3 Q9H4B4 1/20 0.50
MAPKAPK2 P49137 1/20 0.50
DHODH Q02127 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 2/20 0.40
NPC1 O15118 1/20 0.40
HTT P42858 1/20 0.40
RAB9A P51151 1/20 0.40
TP53 P04637 1/20 0.40
EPHX1 P07099 1/20 0.40
NFKB1 P19838 1/20 0.40
EPHX2 P34913 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20684206 0.92 RAB9A (0.46) DAPK3ROCK2CHEK2PIM1PLK1
SCHEMBL3959318 0.91 EPHX1 (0.45) DAPK3ROCK2CHEK2PIM1PLK1
SCHEMBL1241688 0.88 ALDH1A1 (0.52) DAPK3ROCK2CHEK2PIM1PLK1
SCHEMBL13945071 0.88 ALDH1A1 (0.52) DAPK3ROCK2CHEK2PIM1PLK1
SCHEMBL24732190 0.85 MAPT (0.48) SMN1; SMN2LMNANPC1HTTRAB9A
SCHEMBL11470974 0.85 RCE1 (0.47) DAPK3ROCK2CHEK2PIM1PLK1
SCHEMBL14425907 0.83 TDP1 (0.56) DAPK3ROCK2CHEK2PIM1PLK1
SCHEMBL1240997 0.80 NPC1 (0.47) DAPK3ROCK2CHEK2PIM1PLK1
Hydrochloric Acid SCHEMBL11155377 0.80 DAPK3 (0.40) DAPK3ROCK2CHEK2PIM1PLK1
SCHEMBL11153637 0.80 NPC1 (0.56) SMN1; SMN2NPC1HTTRAB9AEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1902106-B1 PRIMER COMPOSITIONS FOR ADHESIVE BONDING SYSTEMS HENKEL CORP (US) 2014-08-20 EP claimed
US-20100151253-A1 Primer Compositions for Adhesive Bonding Systems HENKEL KGAA (DE) 2010-06-17 US claimed
US-6723763-B2 ANAEROBIC ADHESIVE COMPOSITION COMPRISING (METH)ACRYLATE COMPONENT, ANAEROBIC CURE-INDUCING COMPOSITION, AND PHENYLENEDIAMINE-BASED CURE ACCELERATOR HENKEL LOCTITE CORPORATION 2004-04-20 US claimed
US-20030207126-A1 Cure accelerators for anaerobic adhesive compositions LOCTITE CORPORATION 2003-11-06 US claimed
EP-0050472-B1 N,N'-BIS(1-CYCLOHEXYL-1-ETHYL)-P-PHENYLENEDIAMINE AND RUBBER COMPOUNDS CONTAINING THE SAME MONSANTO COMPANY (US) 1984-04-18 EP claimed
EP-0050472-A1 N,N'-bis(1-cyclohexyl-1-ethyl)-p-phenylenediamine and rubber compounds containing the same MONSANTO COMPANY (US) 1982-04-28 EP claimed
US-4297269-A WHEREIN THE DIAMINE IS USED AS A STABILIZER MONSANTO COMPANY (US) 1981-10-27 US claimed
US-9522974-B2 Primer compositions for adhesive bonding systems and coatings HENKEL AG & CO. KGAA (DE) 2016-12-20 US disclosed
EP-2190900-B1 PRIMER COMPOSITIONS FOR ADHESIVE BONDING SYSTEMS AND COATINGS HENKEL AG & CO KGAA (DE) 2016-01-06 EP disclosed
EP-1902106-B1 PRIMER COMPOSITIONS FOR ADHESIVE BONDING SYSTEMS HENKEL CORP (US) 2014-08-20 EP disclosed
US-8288533-B1 Methods for preparing benzoxazines using aqueous solvent HENKEL CORPORATION (US) 2012-10-16 US disclosed
US-20100285309-A1 PRIMER COMPOSITIONS FOR ADHESIVE BONDING SYSTEMS AND COATINGS HENKEL AG & CO. KGAA (DE) 2010-11-11 US disclosed
US-20100151253-A1 Primer Compositions for Adhesive Bonding Systems HENKEL KGAA (DE) 2010-06-17 US disclosed
EP-0050472-B1 N,N'-BIS(1-CYCLOHEXYL-1-ETHYL)-P-PHENYLENEDIAMINE AND RUBBER COMPOUNDS CONTAINING THE SAME MONSANTO COMPANY (US) 1984-04-18 EP disclosed
EP-0050472-B1 N,N'-BIS(1-CYCLOHEXYL-1-ETHYL)-P-PHENYLENEDIAMINE AND RUBBER COMPOUNDS CONTAINING THE SAME MONSANTO COMPANY (US) 1984-04-18 EP disclosed
EP-0050472-A1 N,N'-bis(1-cyclohexyl-1-ethyl)-p-phenylenediamine and rubber compounds containing the same MONSANTO COMPANY (US) 1982-04-28 EP disclosed
EP-0050472-A1 N,N'-bis(1-cyclohexyl-1-ethyl)-p-phenylenediamine and rubber compounds containing the same MONSANTO COMPANY (US) 1982-04-28 EP disclosed
US-4297269-A WHEREIN THE DIAMINE IS USED AS A STABILIZER MONSANTO COMPANY (US) 1981-10-27 US disclosed
US-4297269-A WHEREIN THE DIAMINE IS USED AS A STABILIZER MONSANTO COMPANY (US) 1981-10-27 US disclosed
US-4297269-A WHEREIN THE DIAMINE IS USED AS A STABILIZER MONSANTO COMPANY (US) 1981-10-27 US disclosed