⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11185020 | 0.87 | LMNA (0.41) | — | |
| SCHEMBL14959695 | 0.83 | ACHE (0.48) | — | |
| SCHEMBL29834112 | 0.80 | ACHE (0.54) | — | |
| SCHEMBL87647 | 0.80 | — | — | |
| SCHEMBL345235 | 0.79 | ACHE (0.56) | — | |
| SCHEMBL1524901 | 0.79 | ACHE (0.48) | — | |
| SCHEMBL16486265 | 0.78 | ACHE (0.44) | — | |
| Methyl Alcohol SCHEMBL11130161 | 0.78 | ALDH1A1 (0.46) | — | |
| SCHEMBL2338040 | 0.78 | GAA (0.39) | — | |
| SCHEMBL28815661 | 0.78 | GAA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132481-A1 | INTERLEUKIN-4 GENE EXPRESSION INHIBITORS | AVENTIS PHARMACEUTICALS INC. | 2008-06-05 | — | — | US | claimed |
| EP-1501797-A1 | 3-SUBSTITUTED AMINO-1H-INDOLE-2-CARBOXYLIC ACID AND 3-SUBSTITUTED AMINO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID DERIVATIVES AS INTERLEUKIN-4 GENE EXPRESSION INHIBITORS | Aventis Pharmaceuticals, Inc. (US) | 2005-02-02 | — | — | EP | claimed |
| US-20040006123-A1 | Interleukin-4 gene expression inhibitors | AVENTIS PHARMACEUTICALS INC. | 2004-01-08 | — | — | US | claimed |
| WO-2003091214-A1 | 3-SUBSTITUTED AMINO-1H-INDOLE-2-CARBOXYLIC ACID AND 3-SUBSTITUTED AMINO-BENZO | AVENTIS PHARMACEUTICALS INC. (US) | 2003-11-06 | — | — | WO | claimed |
| CN-113272309-B | Tricyclic inhibitors of hepatitis b virus | 圣拉斐尔医院有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-115836073-A | 1- (5- (2-cyanopyridin-4-yl) oxazole-2-carbonyl) -4-methylhexahydropyrrolo [3,4-B ] pyrrole-5 (1H) -carbonitrile as a USP30 inhibitor for the treatment of mitochondrial dysfunction, cancer and fibrosis | 特殊治疗有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-114555608-A | Oxamide substituted tricyclic inhibitors of hepatitis b virus | 分子遗传国家研究所(INGM) | 2022-05-27 | — | — | CN | disclosed |
| CN-110475777-B | Novel pyrido [2,3-b ] indole compounds for the treatment and prevention of bacterial infections | 豪夫迈·罗氏有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-113272309-A | Tricyclic inhibitors of hepatitis B virus | 圣拉斐尔医院有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-101665647-B | Low emission, high scrub VAE latex paints | CELANESE INT CORP | 2014-08-06 | — | — | CN | disclosed |
| US-20110027379-A1 | Oligo-Ethylene Glycol-Based Polymer Compositions and Methods of Use | CORNELL UNIVERSITY | 2011-02-03 | — | — | US | disclosed |
| EP-2227223-A2 | OLIGO-ETHYLENE GLYCOL-BASED POLYMER COMPOSITIONS AND METHODS OF USE | Medivas, LLC (US) | 2010-09-15 | — | — | EP | disclosed |
| EP-1501797-A1 | 3-SUBSTITUTED AMINO-1H-INDOLE-2-CARBOXYLIC ACID AND 3-SUBSTITUTED AMINO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID DERIVATIVES AS INTERLEUKIN-4 GENE EXPRESSION INHIBITORS | Aventis Pharmaceuticals, Inc. (US) | 2005-02-02 | — | — | EP | disclosed |
| US-20040006123-A1 | Interleukin-4 gene expression inhibitors | AVENTIS PHARMACEUTICALS INC. | 2004-01-08 | — | — | US | disclosed |
| WO-2003091214-A1 | 3-SUBSTITUTED AMINO-1H-INDOLE-2-CARBOXYLIC ACID AND 3-SUBSTITUTED AMINO-BENZO | AVENTIS PHARMACEUTICALS INC. (US) | 2003-11-06 | — | — | WO | disclosed |
| CN-1027165-C | Process for preparing 7-ring substituted-3-quinolone carboxylic acid derivatives | BAYER AG (DE) | 1994-12-28 | — | — | CN | disclosed |
| CN-1039589-A | 7- (1-pyrrolidinyl) -3-quinolone-and 1, 5-naphthyridonecarboxylic acid derivatives and process for preparing same | BAYER AG (DE) | 1990-02-14 | — | — | CN | disclosed |
| EP-0000889-B1 | 3\"-N-DEMETHYL-3\"-N-SUBSTITUTED-4,6-DI-0-(AMINOGLYCOSYL)-1,3-DIAMINOCYCLITOLS, METHODS FOR THEIR PREPARATION AND THEIR APPLICATION AS ANTIBIOTICS | BAYER AG (DE) | 1981-04-29 | — | — | EP | disclosed |
| US-4224315-A | Pseudotrisaccharides and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-23 | — | — | US | disclosed |
| EP-0000889-A1 | 3\"-N-Demethyl-3\"-N-substituted-4,6-di-0-(aminoglycosyl)-1,3-diaminocyclitols, methods for their preparation and their application as antibiotics | BAYER AG (DE) | 1979-03-07 | — | — | EP | disclosed |