Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CPB1 | P15086 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472844 | 1.00 | ALDH1A1 (0.33) | ALDH1A1POLBTLR2TLR1TRPM8 | |
| SCHEMBL11478366 | 0.91 | TRPM8 (0.35) | ALDH1A1POLBTLR2TLR1TRPM8 | |
| SCHEMBL11478376 | 0.91 | TRPM8 (0.35) | ALDH1A1POLBTLR2TLR1TRPM8 | |
| SCHEMBL11446740 | 0.82 | ALDH1A1 (0.34) | ALDH1A1POLBTLR2TLR1DPP8 | |
| SCHEMBL11472843 | 0.78 | PGR (0.33) | ALDH1A1POLB | |
| SCHEMBL11478373 | 0.77 | CNR1 (0.33) | ALDH1A1POLBTRPM8 | |
| SCHEMBL11508178 | 0.77 | TRPM8 (0.36) | ALDH1A1POLBTRPM8HTR2AHTR2C | |
| SCHEMBL11472015 | 0.75 | TRPM8 (0.41) | ALDH1A1TRPM8HTR2AHTR2CHTR2B | |
| SCHEMBL11472017 | 0.75 | TRPM8 (0.41) | ALDH1A1TRPM8HTR2AHTR2CHTR2B | |
| SCHEMBL11548046 | 0.75 | ALDH1A1 (0.38) | ALDH1A1POLBCPB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4199589-A | N-(2-Aminocycloheptyl)acylanilides and methods to treat depression | SZMUSZKOVICZ JACOB (US) | 1980-04-22 | — | — | US | disclosed |
| US-4172898-A | N-(2-aminocycloheptyl)acylanilides | THE UPJOHN COMPANY (US) | 1979-10-30 | — | — | US | disclosed |
| US-4156015-A | N-(2-Aminocyclopentyl)acylanilides and treating depression | THE UPJOHN COMPANY (US) | 1979-05-22 | — | — | US | disclosed |