Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11485588 | 0.84 | MEN1 (0.50) | MEN1KMT2ACA12CYP1A2CYP3A4 | |
| SCHEMBL29048576 | 0.81 | MEN1 (0.72) | MEN1KMT2ACA12CYP1A2CYP3A4 | |
| SCHEMBL12406975 | 0.80 | KMT2A (1.00) | MEN1KMT2ACA12CYP1A2CYP3A4 | |
| SCHEMBL7866143 | 0.80 | LMNA (0.59) | MEN1KMT2ACA12CA9L3MBTL1 | |
| SCHEMBL20981435 | 0.78 | MEN1 (0.63) | MEN1KMT2ACA12CYP1A2CYP3A4 | |
| SCHEMBL29128000 | 0.78 | KMT2A (0.72) | MEN1KMT2ACA12CYP1A2CYP3A4 | |
| SCHEMBL5960083 | 0.78 | KMT2A (0.72) | MEN1KMT2ACA12CYP1A2CYP3A4 | |
| SCHEMBL7521985 | 0.78 | KMT2A (0.72) | MEN1KMT2ACA12CYP1A2CYP3A4 | |
| SCHEMBL29540801 | 0.78 | KEAP1 (0.70) | MEN1KMT2ACA12CYP1A2CYP3A4 | |
| SCHEMBL12945183 | 0.77 | KMT2A (0.67) | MEN1KMT2ACA12CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198506-A | INTERMEDIATES FOR THE CORRESPONDING 3-SUBSTITUTED 3-CEPHEM-4-CARBOXYLIC ACIDS | BRISTOL-MYERS COMPANY (US) | 1980-04-15 | — | — | US | disclosed |
| US-4151352-A | CEPHALOSPORINS, BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1979-04-24 | — | — | US | disclosed |
| US-4082912-A | ANTIBACTERIAL | BRISTOL-MYERS COMPANY (US) | 1978-04-04 | — | — | US | disclosed |