SCHEMBL7521985

SCHEMBL7521985

[CH2]c1ccccc1CNS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.72

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.72
MEN1 O00255 2/20 0.72
CA12 O43570 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP3A4 P08684 1/20 0.62
ATM Q13315 1/20 0.62
CA9 Q16790 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
CYP19A1 P11511 1/20 0.56
GAA P10253 2/20 0.54
ALDH1A1 P00352 7/20 0.53
SMN1; SMN2 Q16637 2/20 0.51
LMNA P02545 1/20 0.51
HTT P42858 1/20 0.51
POLB P06746 1/20 0.49
HPGD P15428 1/20 0.49
PKM P14618 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12406975 0.84 KMT2A (1.00) KMT2AMEN1CA12CYP1A2CYP3A4
SCHEMBL5960083 0.81 KMT2A (0.72) KMT2AMEN1CA12CYP1A2CYP3A4
SCHEMBL29048576 0.81 MEN1 (0.72) KMT2AMEN1CA12CYP1A2CYP3A4
SCHEMBL29128000 0.81 KMT2A (0.72) KMT2AMEN1CA12CYP1A2CYP3A4
SCHEMBL28904049 0.81 KMT2A (0.67) KMT2AMEN1CA12CYP1A2CYP3A4
SCHEMBL12945183 0.81 KMT2A (0.67) KMT2AMEN1CA12CYP1A2CYP3A4
SCHEMBL19636715 0.79 MEN1 (0.68) KMT2AMEN1CA12CYP1A2CYP3A4
SCHEMBL7525089 0.78 ALDH1A1 (0.55) KMT2AMEN1CA12GAAALDH1A1
SCHEMBL20981380 0.78 KMT2A (0.67) KMT2AMEN1CA12CYP1A2CYP3A4
SCHEMBL29019312 0.78 KMT2A (0.67) KMT2AMEN1CA12CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1179529-A1 NOVEL HYDROXAMIC ACID DERIVATIVES Daiichi Fine Chemical Co., Ltd. (JP) 2002-02-13 EP disclosed
EP-1038864-A1 NOVEL METALLOPROTEINASE INHIBITORS FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 2000-09-27 EP disclosed