Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | CD38 | P28907 | 3/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6439308 | 0.77 | KMT2A (1.00) | KMT2AMEN1SMN1; SMN2HTTRAB9A | |
| SCHEMBL11541657 | 0.77 | MEN1 (0.76) | KMT2AMEN1SMN1; SMN2HTTRAB9A | |
| SCHEMBL11538736 | 0.76 | KMT2A (0.63) | KMT2AMEN1SMN1; SMN2HTTRAB9A | |
| SCHEMBL11541067 | 0.76 | MEN1 (0.63) | KMT2AMEN1HTTRAB9ANPC1 | |
| SCHEMBL11555544 | 0.75 | KMT2A (0.58) | KMT2AMEN1HTTCD38MAPT | |
| SCHEMBL11557861 | 0.75 | MEN1 (0.61) | KMT2AMEN1SMN1; SMN2HTTCD38 | |
| SCHEMBL11539010 | 0.74 | KMT2A (0.67) | KMT2AMEN1SMN1; SMN2HTTRAB9A | |
| SCHEMBL11537127 | 0.74 | MEN1 (0.67) | KMT2AMEN1SMN1; SMN2CD38ALDH1A1 | |
| SCHEMBL11538807 | 0.74 | KMT2A (0.67) | KMT2AMEN1HTTRAB9ANPC1 | |
| SCHEMBL11535044 | 0.74 | MEN1 (0.78) | KMT2AMEN1SMN1; SMN2HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225724-A | IMMUNOSUPPRESSANT ACTIVITY | WESTWOOD PHARMACEUTICALS, INC. (US) | 1980-09-30 | — | — | US | claimed |