Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489499 | 0.77 | POLB (0.35) | POLBSMN1; SMN2TSHRRAB9A | |
| SCHEMBL11475616 | 0.71 | MLYCD (0.44) | POLBALDH1A1GAAMEN1KMT2A | |
| SCHEMBL14415481 | 0.70 | NPC1 (0.51) | SMN1; SMN2MEN1KMT2ATRPM8RAB9A | |
| SCHEMBL11474569 | 0.68 | TRPM8 (0.44) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11508197 | 0.68 | TRPM8 (0.41) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10625983 | 0.68 | SMN1; SMN2 (0.50) | SMN1; SMN2TRPM8RAB9ANPC1 | |
| SCHEMBL11475533 | 0.68 | SMN1; SMN2 (0.54) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4851994 | 0.62 | TACR1 (0.37) | POLBALDH1A1GAAMEN1KMT2A | |
| SCHEMBL15017515 | 0.62 | DAGLA (0.48) | POLBALDH1A1GAAMEN1KMT2A | |
| SCHEMBL4207496 | 0.61 | TSHR (0.51) | POLBALDH1A1GAASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4186204-A | ANTI-ALLERGIC ACTIVITY | ELI LILLY AND COMPANY (GB) | 1980-01-29 | — | — | US | claimed |
| US-4186204-A | ANTI-ALLERGIC ACTIVITY | ELI LILLY AND COMPANY (GB) | 1980-01-29 | — | — | US | disclosed |