Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11456255 | 0.77 | MEN1 (0.44) | TRPM8SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL11471904 | 0.74 | HTT (0.39) | TSHRMEN1KMT2ACNR2TP53 | |
| SCHEMBL10625983 | 0.74 | SMN1; SMN2 (0.50) | TRPM8SMN1; SMN2NPC1RAB9AALOX5 | |
| SCHEMBL11508197 | 0.73 | TRPM8 (0.41) | TRPM8SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL14415481 | 0.72 | NPC1 (0.51) | TRPM8SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL11465092 | 0.69 | MLYCD (0.49) | TRPM8SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL11474148 | 0.68 | POLB (0.43) | TRPM8SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL4207496 | 0.66 | TSHR (0.51) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL2484986 | 0.64 | PTGIR (0.44) | SMN1; SMN2TSHRMEN1KMT2ATP53 | |
| SCHEMBL20009173 | 0.64 | ALDH1A1 (0.53) | TRPM8TSHRKMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4222946-A | ANTIALLERGEN, HYPERSENSITIVITY | LILLY INDUSTRIES, LIMITED (GB) | 1980-09-16 | — | — | US | disclosed |
| US-4187232-A | ANTIALLERGENS | LILLY INDUSTRIES LIMITED (GB) | 1980-02-05 | — | — | US | disclosed |