SCHEMBL11474151

SCHEMBL11474151

O=C1c2cccc(N(c3ccccc3)c3ccccc3)c2C(=O)c2c(O)ccc(O)c21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.55
MEN1 O00255 8/20 0.55
KMT2A Q03164 8/20 0.55
MAOA P21397 6/20 0.55
EGFR P00533 2/20 0.49
PIM1 P11309 1/20 0.49
TDP1 Q9NUW8 7/20 0.49
ALDH1A1 P00352 7/20 0.49
MAPK1 P28482 6/20 0.49
HPGD P15428 6/20 0.49
ALOX15 P16050 5/20 0.49
HSD17B10 Q99714 5/20 0.49
SMN1; SMN2 Q16637 4/20 0.49
LMNA P02545 4/20 0.49
TSHR P16473 2/20 0.49
MAOB P27338 2/20 0.49
HTT P42858 1/20 0.49
POLB P06746 5/20 0.46
MCL1 Q07820 3/20 0.46
L3MBTL1 Q9Y468 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2062965 0.85 ALDH1A1 (0.62) MAPTMEN1KMT2AMAOAEGFR
SCHEMBL21922853 0.83 MAPT (0.55) MAPTMEN1KMT2AMAOAEGFR
SCHEMBL11601937 0.80 ESR1 (0.47) MAPTMEN1KMT2AMAOAEGFR
SCHEMBL11605486 0.80 MAPT (0.46) MAPTMEN1KMT2AMAOAEGFR
SCHEMBL29120744 0.80 MAPT (0.50) MAPTMEN1KMT2AMAOAEGFR
SCHEMBL21922650 0.78 MAPT (0.53) MAPTMEN1KMT2AMAOAEGFR
SCHEMBL17949360 0.77 MAPT (0.47) MAPTMEN1KMT2AMAOAEGFR
SCHEMBL21922850 0.76 MAPT (0.47) MAPTMEN1KMT2AMAOAEGFR
SCHEMBL30695844 0.75 MAOA (0.86) MAPTMEN1KMT2AMAOAEGFR
SCHEMBL3198327 0.75 MAOA (0.86) MAPTMEN1KMT2AMAOAEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190161617-A1 METHOD FOR PREPARING PHENYLAMINOHYDROXYANTHRAQUINONES LANXESS DEUTSCHLAND GMBH (DE) 2019-05-30 US claimed
CN-109836343-B Process for preparing phenylaminohydroxyanthraquinones 朗盛德国有限责任公司 2022-02-11 CN disclosed
CN-109836343-B Process for preparing phenylaminohydroxyanthraquinones 朗盛德国有限责任公司 2022-02-11 CN disclosed
US-20190161617-A1 METHOD FOR PREPARING PHENYLAMINOHYDROXYANTHRAQUINONES LANXESS DEUTSCHLAND GMBH (DE) 2019-05-30 US disclosed
US-20190161617-A1 METHOD FOR PREPARING PHENYLAMINOHYDROXYANTHRAQUINONES LANXESS DEUTSCHLAND GMBH (DE) 2019-05-30 US disclosed
US-4231918-A THIOINDIGO OR DIOXAZINE PIGMENT AND DYE CIBA-GEIGY CORPORATION (US) 1980-11-04 US disclosed
US-4141881-A PERYLENE-3,4,9,10-TETRACARBOXYLIC PIGMENT MIXTURE WITH DYE CIBA-GEIGY CORPORATION (US) 1979-02-27 US disclosed
US-4094839-A Preparations for coloring molten thermoplastic polymers CIBA-GEIGY CORPORATION (US) 1978-06-13 US disclosed
US-4093584-A Process for the mass coloration or whitening of linear polyesters CIBA-GEIGY CORPORATION (US) 1978-06-06 US disclosed