Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | NSD2 | O96028 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 4/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2062965 | 0.93 | ALDH1A1 (0.62) | MAPTL3MBTL1ALDH1A1MAPK1LMNA | |
| SCHEMBL21923977 | 0.92 | MAPT (0.46) | MAPTL3MBTL1ALDH1A1MAPK1LMNA | |
| SCHEMBL16684001 | 0.90 | MAPT (0.47) | MAPTL3MBTL1ALDH1A1MAPK1LMNA | |
| SCHEMBL21922853 | 0.87 | MAPT (0.55) | MAPTL3MBTL1ALDH1A1MAPK1LMNA | |
| SCHEMBL29120744 | 0.87 | MAPT (0.50) | MAPTL3MBTL1ALDH1A1MAPK1LMNA | |
| SCHEMBL17949360 | 0.84 | MAPT (0.47) | MAPTL3MBTL1ALDH1A1MAPK1LMNA | |
| SCHEMBL21922850 | 0.80 | MAPT (0.47) | MAPTL3MBTL1ALDH1A1MAPK1LMNA | |
| SCHEMBL6925372 | 0.80 | L3MBTL1 (0.60) | MAPTL3MBTL1ALDH1A1MAPK1LMNA | |
| Anthraquinone SCHEMBL9545478 | 0.80 | MEN1 (0.63) | MAPTL3MBTL1ALDH1A1MAPK1LMNA | |
| SCHEMBL25580011 | 0.79 | HNF4A (0.35) | MAPTL3MBTL1ALDH1A1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020083327-A1 | ORGANIC COMPOUND CONTAINING SPIROBIFLUORENE STRUCTURE AND APPLICATION THEREOF IN OLED DEVICE | 常州强力电子新材料股份有限公司 | 2020-04-30 | — | — | WO | disclosed |