Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945827 | 0.84 | CA12 (0.35) | EGFRATRCA12CA1CA2 | |
| SCHEMBL28018277 | 0.81 | P2RX7 (0.34) | CA12CA1CA2CA9POLB | |
| SCHEMBL1712644 | 0.81 | ABL1 (0.42) | CA12CA1CA2CA9POLB | |
| SCHEMBL27768243 | 0.80 | NR3C2 (0.34) | EGFRCA12CA1CA2CA9 | |
| SCHEMBL28791104 | 0.80 | CA12 (0.33) | EGFRCA12CA1CA2CA9 | |
| SCHEMBL27697960 | 0.80 | CA12 (0.36) | EGFRCA12CA1CA2CA9 | |
| SCHEMBL4322089 | 0.77 | MAPK1 (0.32) | — | |
| SCHEMBL27383305 | 0.76 | EGFR (0.35) | EGFRCA12CA1CA2CA9 | |
| SCHEMBL27833658 | 0.75 | MAPT (0.36) | POLBKMT2AMEN1 | |
| SCHEMBL27806654 | 0.75 | CES2 (0.52) | POLBKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009762-A1 | Substituted N-benzoyl-N'-tert.-alcoxycarbonylphenyl(thio)ureas, methods for their preparation and their use as insecticides | BAYER AG (DE) | 1980-04-16 | — | — | EP | disclosed |