Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 4/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945827 | 0.84 | CA12 (0.35) | CA12CA1CA2CA9CA14 | |
| SCHEMBL1355068 | 0.81 | ALDH1A1 (0.41) | CA12CA1CA2CA9CA14 | |
| SCHEMBL27697960 | 0.80 | CA12 (0.36) | CA12CA1CA2CA9CA14 | |
| SCHEMBL28791104 | 0.80 | CA12 (0.33) | CA12CA1CA2CA9CA14 | |
| SCHEMBL11474155 | 0.80 | EGFR (0.35) | NR3C2CA12CA1CA2CA9 | |
| SCHEMBL27383305 | 0.76 | EGFR (0.35) | CA12CA1CA2CA9CA14 | |
| SCHEMBL27833658 | 0.75 | MAPT (0.36) | POLBMAPT | |
| SCHEMBL4216164 | 0.75 | CES2 (0.52) | POLBMAPTADRB2ADRB1ADRB3 | |
| SCHEMBL28296044 | 0.75 | GRM6 (0.35) | NR3C2CA12CA1CA2CA9 | |
| SCHEMBL1206852 | 0.74 | KMT2A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101626686-A | 3-substituent-1, 2, 3-benzotriazinone compounds for improving glutaminic synaptic responses | CORTEX PHARMA INC | 2010-01-13 | — | — | CN | disclosed |