Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11485804 | 0.90 | PTGES (0.53) | PTGESHPGDRECQLALDH1A1LMNA | |
| SCHEMBL11483877 | 0.84 | HPGD (0.50) | PTGESHPGDRECQLALDH1A1LMNA | |
| SCHEMBL11469614 | 0.83 | PTGES (0.48) | PTGESHPGDRECQLALDH1A1LMNA | |
| SCHEMBL11468302 | 0.81 | NPSR1 (0.58) | PTGESHPGDRECQLALDH1A1LMNA | |
| SCHEMBL11484216 | 0.81 | PTGES (0.46) | PTGESHPGDRECQLGPR84ALDH1A1 | |
| SCHEMBL11477119 | 0.80 | PTGES (1.00) | PTGESTP53MAPT | |
| SCHEMBL11485827 | 0.79 | PTGES (0.79) | PTGESHPGDRECQLLMNATP53 | |
| SCHEMBL11485871 | 0.79 | PTGES (0.53) | PTGESHPGDRECQLALDH1A1LMNA | |
| SCHEMBL31582268 | 0.79 | PTGES (0.63) | PTGESHPGDRECQLGPR84ALDH1A1 | |
| SCHEMBL11479740 | 0.78 | PTGES (0.73) | PTGESLMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190725-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4021553-A | 5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1977-05-03 | — | — | US | disclosed |