Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11483877 | 0.88 | HPGD (0.50) | NPSR1RECQLHPGDPTGESALDH1A1 | |
| SCHEMBL11485804 | 0.85 | PTGES (0.53) | NPSR1RECQLHPGDPTGESALDH1A1 | |
| SCHEMBL11479414 | 0.84 | HPGD (0.44) | NPSR1RECQLHPGDPTGESALDH1A1 | |
| SCHEMBL11470010 | 0.82 | NPSR1 (0.64) | NPSR1RECQLHPGDALDH1A1POLB | |
| SCHEMBL11475303 | 0.81 | PTGES (0.67) | NPSR1RECQLHPGDPTGESALDH1A1 | |
| SCHEMBL10814630 | 0.79 | NPSR1 (0.64) | NPSR1RECQLHPGDPTGESALDH1A1 | |
| SCHEMBL11468269 | 0.79 | ALDH1A1 (0.41) | NPSR1RECQLHPGDALDH1A1LMNA | |
| SCHEMBL11470519 | 0.78 | LMNA (0.41) | NPSR1RECQLHPGDPTGESALDH1A1 | |
| SCHEMBL11870230 | 0.78 | ALDH1A1 (0.40) | NPSR1RECQLHPGDALDH1A1LMNA | |
| SCHEMBL1304925 | 0.78 | ALDH1A1 (0.40) | NPSR1RECQLHPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190725-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4021553-A | 5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1977-05-03 | — | — | US | disclosed |